Endocrine Abstracts

Introduction: 46 XY Disorders of Sex Development (46, XY DSD) is defined by the presence of female or incompletely virilized external genitalia in a 46, XY individual. 17β-hydroxysteroid dehydrogenase 3 (17βHSD3) deficiency is one of the causes for testosterone biosynthetic defects. It leads to defective conversion of androstenedione to testosterone. 17βHSD3 deficiency can present with female phenotype with inguinal hernias at birth, clitoromegaly during infancy...

Background: Hirsutism is a common and disturbing complaint among women attending endocrine clinics. It is caused by androgen excess and when severe, might progress to virilization. Virilizing adrenal tumors are a rare cause of hirsutism.Case presentation: A 14 year old girl presented with primary amenorrhea, poor breast development (Tanner stage B1), hirsutism (Ferriman-gallwey score, FGS of 12/36) clitoromegaly (clitoral index >200 mm2). ...